Why does avelox cause tendonitis

Skip to main content. Human regulatory Overview Research and development Marketing authorisation Post-authorisation Herbal products. Veterinary regulatory Overview Research and development Marketing authorisation Post-authorisation. Disabling and potentially permanent side effects lead to suspension or restrictions of quinolone and fluoroquinolone antibiotics. Restrictions on the use of fluoroquinolone antibiotics will mean that they should not be used: to treat infections that might get better without treatment or are not severe such as throat infections ; to treat non-bacterial infections, e.

Information for patients Fluoroquinolone medicines which contain ciprofloxacin, levofloxacin, lomefloxacin, moxifloxacin, norfloxacin, ofloxacin, pefloxacin, prulifloxacin and rufloxacin can cause long-lasting, disabling and potentially permanent side effects involving tendons, muscles, joints and the nervous system.

These serious side effects include inflamed or torn tendon, muscle pain or weakness, and joint pain or swelling, walking difficulty, feeling pins and needles, burning pain, tiredness, depression, problems with memory, sleeping, vision and hearing, and altered taste and smell. Tendon swelling and injury may occur within 2 days of starting treatment with a fluoroquinolone but may even occur several months after stopping treatment.

Stop taking a fluoroquinolone medicine and contact your doctor at once in the following cases: at the first sign of tendon injury, such as tendon pain or swelling — rest the painful area; if you get pain, feel pins and needles, tingling, tickling, numbness or burning, or weakness especially in the legs or arms; if you get swelling in the shoulder, arms or legs, have walking difficulty, feel tired or depressed or have problems with your memory or with sleeping or you notice changes with your vision, taste, smell or hearing.

You and your doctor will decide if you can continue treatment or if you need to take another type of antibiotic. You may be more prone to joint pain or swelling or tendon damage if you are aged over 60 years, your kidneys do not work well or you have received organ transplantation.

Speak with your doctor if you are taking a corticosteroid medicines such as hydrocortisone and prednisolone or need to have treatment with a corticosteroid. You may be especially prone to tendon damage if you are taking a corticosteroid and a fluoroquinolone medicine at the same time. You should not take a fluoroquinolone medicine if you have ever had a serious side effect with a fluoroquinolone or a quinolone medicine and you should speak with your doctor immediately.

If you have any questions or concerns about your medicines, speak to your doctor or pharmacist. Information for healthcare professionals Fluoroquinolones are associated with prolonged up to months or years , serious, disabling and potentially irreversible drug reactions affecting several, sometimes multiple, systems, organ classes and senses.

If you have low potassium levels in the blood, moxifloxacin may increase your risk of having a fast, slow or irregular heartbeat, loss of consciousness, or fainting spells. If these symptoms occur, tell your doctor right away.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have itching, hives, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you take this medicine.

Serious side effects can occur during treatment with this medicine and can sometimes occur without warning. Possible warning signs include black, tarry stools, blistering, peeling, or loosening of the skin, bloody or cloudy urine, chills, decreased urination, diarrhea, fever, joint or muscle pain, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, severe stomach pain, skin rash, swelling of the face, fingers, feet, or lower legs, unusual bleeding or bruising, unusual weight gain, or yellow skin or eyes.

Check with your doctor immediately if you notice any of these warning signs. Moxifloxacin may lower the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently.

Be careful when using sharp objects, including razors and fingernail clippers. Moxifloxacin may cause diarrhea, and in some cases it can be severe.

It may occur 2 months or more after you stop taking this medicine. Do not take any medicine to treat diarrhea without checking first with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. Taking moxifloxacin may affect your brain or nervous system and cause serious side effects.

This can occur after the first dose of moxifloxacin. Tell your doctor if you have or have ever had seizures, epilepsy, cerebral arteriosclerosis narrowing of blood vessels in or near the brain that can lead to stroke or ministroke , stroke, changed brain structure, or kidney disease.

If you experience any of the following symptoms, stop taking moxifloxacin and call your doctor immediately: seizures; tremors; dizziness; lightheadedness; headaches that won't go away with or without blurred vision ; difficulty falling asleep or staying asleep; nightmares; not trusting others or feeling that others want to hurt you; hallucinations seeing things or hearing voices that do not exist ; thoughts or actions toward hurting or killing yourself; memory problems; feeling restless, anxious, nervous, depressed, or confused, or other changes in your mood or behavior.

Taking moxifloxacin may worsen muscle weakness in people with myasthenia gravis a disorder of the nervous system that causes muscle weakness and cause severe difficulty breathing or death.

Tell your doctor if you have myasthenia gravis. Your doctor may tell you not to take moxifloxacin. If you have myasthenia gravis and your doctor tells you that you should take moxifloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment. Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin treatment with moxifloxacin.

Read the information carefully and ask your doctor or pharmacist if you have any questions. Moxifloxacin is used to treat certain infections caused by bacteria such as pneumonia, and skin, and abdominal stomach area infections. Moxifloxacin is also used to prevent and treat plague a serious infection that may be spread on purpose as part of a bioterror attack. Moxifloxacin may also be used to treat bronchitis or sinus infections but should not be used for these conditions if there are other treatment options available.

Moxifloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause infections. Antibiotics such as moxifloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Moxifloxacin comes as tablet to take by mouth.

It is usually taken with or without food once a day for 5 to 21 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take moxifloxacin. Take moxifloxacin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take moxifloxacin exactly as directed.

Do not take more or less of it or take it more often than prescribed by your doctor. You should begin to feel better during the first few days of treatment with moxifloxacin. If your symptoms do not improve or if they get worse, call your doctor. Take moxifloxacin until you finish the prescription, even if you feel better. If you stop taking moxifloxacin too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Moxifloxacin is also sometimes used to treat tuberculosis TB , certain sexually transmitted diseases, and endocarditis infection of the heart lining and valves when other medications cannot be used.

Moxifloxacin also may be used to treat or prevent anthrax a serious infection that may be spread on purpose as part of a bioterror attack in people who may have been exposed to anthrax germs in the air if other medications are not available for this purpose.